Capitalization is a top-priority process in ensuring the development of the economy in the leading countries of the world. But, in the strategy and policy of development of the economy of Ukraine and its regions, unfortunately, there is no clear line of action and systematic measures in the direction of capitalization of various forms of capital in the economy. However, only the well-grounded strategy of capitalization of economies of the regions of Ukraine is capable to overcome the set of economic and social problems in our country. The purpose of this article is to substantiate the strategic guidelines of capitalization of the economies of the regions of Ukraine. The methodological base of the research was the developments of economic science according to the study of national economics, regional development, regional economy and capitalization. The objective necessity and urgency of increasing the level of capitalization of the economies of regions of Ukraine is substantiated. The typology of capitalization of the economies of the regions of the state is developed according to the levels of intensity of such processes as accumulation of capital, investment of capital, creation and distribution of added value, which determine and comprehensively characterize the capitalization of the region’s economy. Differentiated approach to the development of strategic guidelines of capitalization of the economies of the regions of Ukraine which is based on the type and level of capitalization of the economy of each of them is proposed. Differentiated approach allows to take into account the initial conditions (the intensity of processes of capital accumulation, the intensity of capital investment processes, the intensity of the processes of creation of added value and optimal distribution of it) and individual needs of the region and purposefully ensure the capitalization of strengths and overcome the weaknesses of development of economies of the regions. The strategic guidelines of capitalization of the economies of each region of Ukraine are determined, in particular, for the city of Kyiv – maintaining the achieved level of capitalization of the region’s economy and its enhancement; for Dnipropetrovsk Oblast – region’s economy restructuring; for Kyiv Oblast – efficiency of the formation and usage of capital; for the other regions of Ukraine – budget supporting, identification of potential sources of the capital and their effective usage. The key dominants of strategic guidelines of capitalization of the economies of the regions of Ukraine are considered. The conducted research allows to choose the most acceptable strategic guideline of capitalization of the economy to everyone regions of Ukraine. The capitalization of the economies of the regions of Ukraine contributes to the capitalization of national economics and to the increasing the level of its competitiveness. 

capitalization, regional economics, strategic guidelines, capital of region, capital accumulation, capital investment, creation and distribution of value added