Key contradictions which are generated by monopolization of capital on the global stage of international economy development have been studied. It has been proved that they are based on the conflicts of the interests of international monopolies and other participants of the global economic system. The aforementioned stipulates radical reorganization of operating system of institutional support of global economic development in order to harmonize interests of main subjects of international economic relations. 

global monopolization of capital, monopolistic structures, global expansion, global competitiveness, inequality of capital accumulation, mergers and acquisitions, national economic sovereignty, international contingent of employed workers